Macules Causes, Treatments and More
Article Sources
- 1. Julia Benedetti, et al. 'Description of Skin Lesions - Dermatologic Disorders.' Merck Manuals Professional Edition, Merck Manuals, www.merckmanuals.com/professional/dermatologic-disorders/approach-to-the-dermatologic-patient/description-of-skin-lesions
- 2. Plensdorf, Scott, et al. 'Pigmentation Disorders: Diagnosis and Management.' American Family Physician, 15 Dec. 2017, www.aafp.org/afp/2017/1215/p797.html
- 3. Madireddy, Sowmya. 'Hypopigmented Macules.' StatPearls /[Internet/]., U.S. National Library of Medicine, 9 Oct. 2020, www.ncbi.nlm.nih.gov/books/NBK563245/
- 4. Stulberg, Daniel L., et al. 'Common Hyperpigmentation Disorders in Adults: Part I. Diagnostic Approach, Cafe Au Lait Macules, Diffuse Hyperpigmentation, Sun Exposure, and Phototoxic Reactions.' American Family Physician, 15 Nov. 2003, www.aafp.org/afp/2003/1115/p1955.html
- 5. Toledo Peral, Cinthya Lourdes, et al. 'An Application for Skin Macules Characterization Based on a 3-Stage Image-Processing Algorithm for Patients with Diabetes.' Journal of Healthcare Engineering, Hindawi, 16 Dec. 2018, www.hindawi.com/journals/jhe/2018/9397105/
- 6. 'Achromic Naevus.' Achromic Naevus | DermNet NZ, www.dermnetnz.org/topics/achromic-naevus/
- 7. Jha, Suman K. 'Cafe Au Lait Macules.' StatPearls /[Internet/]., U.S. National Library of Medicine, 16 Nov. 2020, www.ncbi.nlm.nih.gov/books/NBK557492/
Systemic Disorders
CALMs are sometimes associated with genetic disorders. They occur in 95 percent of people affected by neurofibromatosis. Other potential genetic disorders include Silver-Russell syndrome, McCune-Albright syndrome, ring chromosome syndrome, tuberous sclerosis, Bloom syndrome and a group of genetic disorders called constitutional mismatch repair deficiencies.
Macules that may indicate a genetic disorder usually appear as multiple spots. A CALM with diffuse coloration may develop with other systemic disorders, such as Addison's disease or hypothyroidism.7Jha, Suman K. ‘Cafe Au Lait Macules.’ StatPearls /[Internet/]., U.S. National Library of Medicine, 16 Nov. 2020, www.ncbi.nlm.nih.gov/books/NBK557492/
Advertisement
