10 Causes of Geographic Tongue
Cause #8: Chronic Granulomatous Disease
Chronic granulomatous disease is also known as chronic granulomatous disorder, Quie syndrome, or Bridges–Good syndrome. It refers to a group of hereditary disorders where the cells of the immune system are unable to form reactive oxygen compounds that function to kill ingested pathogens. This results in the formation of granulomata (a collection of immune cells that walls off substances that the immune system is unable to eliminate) in various organs.
Patients with chronic granulomatous disease will experience recurrent infections due to their reduced capacity to fight organisms that cause disease. Geographic tongue has been reported in association with chronic granulomatous disease.
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