Esophageal Cancer Causes
Reviewed: Dr. Mera
8. Tylosis
Tylosis is a rare hereditary disease that is caused by a genetic mutation. This condition causes the focal thickening of the skin of the hands and feet (hyperkeratosis). Furthermore, it is associated with a very high risk of developing esophageal squamous cell carcinoma (40% to 90% by the age of 70 years).
Patients with tylosis should undergo screening for esophageal cancer after twenty years of age.
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