What Is MS?
Reviewed: Dr. Gromatzky
5. Categories
MS can be categorized based on the frequency of relapses, lesion development, and time to disease progression. It can therefore be divided into relapsing remitting MS (RRMS) where there are recurrent attacks where neurologic deficits appear in different parts and resolve in a short duration, secondary progressive MS (SPMS) where there is progressive neurologic decline without periods of remission, primary progressive MS (PPMS) where there is no remission and progression of disability from the onset, and clinically isolated syndrome (CIS) where there is an attack suggestive of demyelination but does not fulfill the criteria for MS.
It is estimated that 30% to 70% of individuals with CIS eventually develop MS.
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