What Is Erythema Nodosum?
2. What Causes Erythema Nodosum
If your doctor tells you that he or she doesn’t know what caused your EN, there’s probably truth to that statement. This isn’t to say that it has no cause; it simply means that most causes of EN — up to 55% — cannot be determined.
EN can be triggered by many diseases that provoke your immune system, such as strep infections, tuberculosis, and autoimmune conditions. In rare cases, EN can be triggered by a medication like an antibiotic or a new birth control pill.
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