What Is Bullous Pemphigoid?
2. What Causes Bullous Pemphigoid?
Pemphigoid is the result of a malfunctioning immune system. When the immune system is in good working order, it fights off potentially harmful foreign substances, such as viruses and bacteria. However, when it malfunctions, it may mistake certain parts of your body, such as tissue, for a harmful foreign substance.
In this condition, the immune system develops immune proteins (autoantibodies) that mistakenly attack skin structures that connect the epidermis (outer layer of the skin) with the dermis (inner layer). As a result, an inflammatory process of the skin takes place and the skin lesions of bullous pemphigoid appear.
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