What Is Anaphylaxis?
Reviewed: Dr. Gromatzky
3. How Does Anaphylaxis Develop?
When an allergic person is exposed to an allergen, numerous chemical reactions occur. Immunoglobulin E, or IgE, reaction involves the release of chemical mediators. A process called degranulation also happens in certain cells; specifically, basophils and mast cells.
The process is more complicated than described here. The result of this inflammatory response is vasodilation (the widening of blood vessels) reduced blood pressure, and increased heart rate. This will cause less blood flow to vital organs. In addition, parts of the lungs will also constrict making it hard to breath.
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