10 Polymyositis Symptoms
Reviewed: Dr. Mera
Symptom #5: Loss of Appetite
Loss of appetite or anorexia is a common and non-specific symptom that can be seen in various conditions. In infection, it is thought to have occurred as part of the acute phase response where it is triggered by the various components of the bacterial cell walls, DNA, viral RNA, and viral glycoproteins.
It can also be due to proinflammatory cytokines as it indirectly increases the production of leptin which contributes to appetite loss. Some of the causes of anorexia include atypical pneumonia, anxiety, appendicitis, cancer, chronic kidney disease, heart failure, dementia, dehydration, hypothyroidism, metabolic disorders, depression, and more.
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