Macules Causes, Treatments and More

By errol
Reviewed: dr. stavarache
Article Sources Article Sources
  • 1. Julia Benedetti, et al. 'Description of Skin Lesions - Dermatologic Disorders.' Merck Manuals Professional Edition, Merck Manuals,
  • 2. Plensdorf, Scott, et al. 'Pigmentation Disorders: Diagnosis and Management.' American Family Physician, 15 Dec. 2017,
  • 3. Madireddy, Sowmya. 'Hypopigmented Macules.' StatPearls /[Internet/]., U.S. National Library of Medicine, 9 Oct. 2020,
  • 4. Stulberg, Daniel L., et al. 'Common Hyperpigmentation Disorders in Adults: Part I. Diagnostic Approach, Cafe Au Lait Macules, Diffuse Hyperpigmentation, Sun Exposure, and Phototoxic Reactions.' American Family Physician, 15 Nov. 2003,
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Medical Expert Medical Expert

Hypopigmented Macules

Hypopigmented macules are lighter colored than surrounding skin. The condition is sometimes called hypomelanosis because it's caused by decreased melanin production. Most hypopigmented macules are benign, although they may occur with a systemic disease in some cases.

Vitiligo is a skin condition associated with hypopigmented macules. The condition occurs when melanocytes in the skin die or stop producing pigment. Macules may affect any area of the body, including the hair and inside the mouth, and discolored patches may multiply or grow larger over time.3Madireddy, Sowmya. ‘Hypopigmented Macules.’ StatPearls /[Internet/]., U.S. National Library of Medicine, 9 Oct. 2020,


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