What Is MS?
2. Etiology
Since the cause of MS is unknown, there are several hypotheses regarding what may contribute to the development of the condition. Studies on twins with MS have suggested that there may be a genetic factor for MS. Individuals with first-degree family members with MS have 7 times higher risk compared to the general population.
It is also observed that MS is less common among individuals who live nearer to the equatorial regions of the world. Another theory would be regarding a viral infection that may activate the T-cells that attack the myelin sheath. The development of MS has been associated with an Epstein Barr virus infection. Other theories include low vitamin D levels and chronic cerebrospinal venous insufficiency.
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